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Article

DHOEM: a statistical simulation software for simulating new markers in real SNP marker data.

BMC bioinformatics - 3 Dec 2015

Jacquin Laval, Cao Tuong-Vi, Grenier Cécile, Ahmadi Nourollah

Abstract excerpt

BACKGROUND: Numerous simulation tools based on specific assumptions have been proposed to simulate populations. Here we present a simulation tool named DHOEM (densification of haplotypes by loess regression and maximum likelihood) which is free from population assumptions and simulates new markers in real SNP marker data. The main objective of DHOEM is to generate a new population, which incorporates real and...

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PMID: 26634451
DOI: 10.1186/s12859-015-0830-7
PMCID: PMC4669601

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MAF

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