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Article

Maximum likelihood estimation of quantitative trait loci parameters with the aid of genetic markers using a standard statistical package.

Computer applications in the biosciences : CABIOS - 1 Sept 1994

Elkind Y, Nir B, Weller J I

Abstract excerpt

Consistent parameter estimates of quantitative trait loci linked to genetic markers can be derived by maximum likelihood methodology. For many experimental designs of interest, parameter estimates and their standard errors can be obtained by program LE of BMDP, which uses the Newton-Raphson method of iteration. Program LE was tested on data simulated for a backcross between two inbred lines. A single quantitative...

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Identifiers

PMID: 7828067
DOI: 10.1093/bioinformatics/10.5.513

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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