Article
Instrumental variable approaches to identifying the causal effect of educational attainment on dementia risk.
Annals of epidemiology - 1 Jan 2016
Nguyen Thu T, Tchetgen Tchetgen Eric J, Kawachi Ichiro, Gilman Stephen E, Walter Stefan, Liu Sze Y, Manly Jennifer J, Glymour M Maria
Abstract excerpt
PURPOSE: Education is an established correlate of cognitive status in older adulthood, but whether expanding educational opportunities would improve cognitive functioning remains unclear given limitations of prior studies for causal inference. Therefore, we conducted instrumental variable (IV) analyses of the association between education and dementia risk, using for the first time in this area, genetic variants...
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