Article
Association Between Vitamin D Receptor rs731236 (Taq1) Polymorphism and Risk for Restless Legs Syndrome in the Spanish Caucasian Population.
Medicine - 1 Nov 2015
Jiménez-Jiménez Félix Javier, García-Martín Elena, Alonso-Navarro Hortensia, Martínez Carmen, Zurdo Martín, Turpín-Fenoll Laura, Millán-Pascual Jorge, Adeva-Bartolomé Teresa, Cubo Esther, Navacerrada Francisco, Rojo-Sebastián Ana, Rubio Lluisa, Ortega-Cubero Sara, Pastor Pau, Calleja Marisol, Plaza-Nieto José Francisco, Pilo-De-La-Fuente Belén, Arroyo-Solera Margarita, García-Albea Esteban, Agúndez José A G
Abstract excerpt
Several recent works suggest a possible role of vitamin D deficiency in the etiology or restless legs syndrome (RLS). We analyzed the possible relationship of 2 common single nucleotide polymorphisms (SNPs) in the vitamin D3 receptor (VDR) gene with the risk for RLS.We studied the genotype and allelic variant frequencies of VDR rs2228570 and VDR rs731236 SNPs in 205 RLS patients and 445 healthy controls using a...
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