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Article

Serum bilirubin concentration is modified by UGT1A1 haplotypes and influences risk of type-2 diabetes in the Norfolk Island genetic isolate.

BMC genetics - 2 Dec 2015

Benton M C, Lea R A, Macartney-Coxson D, Bellis C, Carless M A, Curran J E, Hanna M, Eccles D, Chambers G K, Blangero J, Griffiths L R

Abstract excerpt

BACKGROUND: Located in the Pacific Ocean between Australia and New Zealand, the unique population isolate of Norfolk Island has been shown to exhibit increased prevalence of metabolic disorders (type-2 diabetes, cardiovascular disease) compared to mainland Australia. We investigated this well-established genetic isolate, utilising its unique genomic structure to increase the ability to detect related genetic...

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Identifiers

PMID: 26628212
DOI: 10.1186/s12863-015-0291-z
PMCID: PMC4667444

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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