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Article

Impaired function of regulatory T cells in patients with psoriasis is mediated by phosphorylation of STAT3.

Journal of dermatological science - 1 Feb 2016

Yang Luting, Li Bing, Dang Erle, Jin Liang, Fan Xueli, Wang Gang

Abstract excerpt

BACKGROUND: Psoriasis is a T cell-mediated chronic inflammatory skin disease. Regulatory T cells (Tregs) are crucial in suppressing immune response to maintain the immune balance. Wheras Tregs from psoriatic patients showed poorly activity in suppressing activation of responder T cells (Tresp), the mechanisms involved in this process are still unknown. OBJECTIVES: In this study, we investigated the possible role...

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Source

Identifiers

PMID: 26627723
DOI: 10.1016/j.jdermsci.2015.11.007

Genes

STAT3
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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