Article
Population genetic structure and natural selection of apical membrane antigen-1 in Plasmodium vivax Korean isolates.
Malaria journal - 16 Nov 2015
Kang Jung-Mi, Lee Jinyoung, Cho Pyo-Yun, Moon Sung-Ung, Ju Hye-Lim, Ahn Seong Kyu, Sohn Woon-Mok, Lee Hyeong-Woo, Kim Tong-Soo, Na Byoung-Kuk
Abstract excerpt
BACKGROUND: Plasmodium vivax apical membrane antigen-1 (PvAMA-1) is a leading candidate antigen for blood stage malaria vaccine. However, antigenic variation is a major obstacle in the development of an effective vaccine based on this antigen. In this study, the genetic structure and the effect of natural selection of PvAMA-1 among Korean P. vivax isolates were analysed. METHODS: Blood samples were collected from...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
