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Article

OVOL2, an Inhibitor of WNT Signaling, Reduces Invasive Activities of Human and Mouse Cancer Cells and Is Down-regulated in Human Colorectal Tumors.

Gastroenterology - 1 Mar 2016

Ye Guo-Dong, Sun Guang-Bin, Jiao Peng, Chen Chen, Liu Qing-Feng, Huang Xiao-Li, Zhang Rui, Cai Wang-Yu, Li Sheng-Nan, Wu Jia-Fa, Liu Yun-Jia, Wu Rong-Si, Xie Yuan-Yuan, Chan Err-Cheng, Liou Yih-Cherng, Li Bo-An

Abstract excerpt

BACKGROUND & AIMS: Activation of WNT signaling promotes the invasive activities of several types of cancer cells, but it is not clear if it regulates the same processes in colorectal cancer (CRC) cells, or what mechanisms are involved. We studied the expression and function of OVOL2, a member of...

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Source

Identifiers

PMID: 26619963
DOI: 10.1053/j.gastro.2015.11.041

Genes

OVOL2
TCF4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-26619963-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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