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Article

SNP rs7430456 mediated LINC00578 drives triple negative breast cancer through regulating miR-143-5p expression.

Hereditas - 17 Jul 2026

Zhai Jing, Wu Wei, Mao Xiaoyun, Wu Lianjun

Abstract excerpt

BACKGROUND: A large number of cancer-related single-nucleotide polymorphisms (SNPs) are distributed in the genomic regions of long non-coding RNAs (lncRNAs), yet the mechanisms linking them to cancer risk have not been fully clarified so far. This study explored LINC00578 rs7430456's association with breast cancer susceptibility and LINC00578's role/mechanism in triple-negative breast cancer (TNBC). METHODS: A...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 42469927
DOI: 10.1186/s41065-026-00705-7
PMCID: PMC13523219

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SNP rs7430456 mediated LINC00578 drives triple negative breast cancer through regulating miR-143-5p expression.PMID 42469927Read ↗

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