Article
miR-503-3p promotes epithelial-mesenchymal transition in breast cancer by directly targeting SMAD2 and E-cadherin.
Journal of genetics and genomics = Yi chuan xue bao - 20 Feb 2017
Zhao Zitong, Fan Xinyi, Jiang Lanfang, Xu Zhongqiu, Xue Liyan, Zhan Qimin, Song Yongmei
Abstract excerpt
Although progress in clinical and basic research has significantly increased our understanding of breast cancer, little is known about the molecular mechanism underlying breast cancer metastasis. Identification of effective therapeutic targets to prevent breast cancer metastasis is urgently needed. The function of miR-503-3p has been investigated in other cancers, but its role in breast cancer remains undefined....
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