Article
Role of G-protein coupled receptor kinase 5 gene in cognitive impairment in Parkinson's disease.
Psychiatry research - 30 Dec 2015
Nicoletti Giuseppe, De Luca Vincenzo, Tarantino Patrizia, Gagliardi Monica, Iannello Grazia, Novellino Fabiana, Morelli Maurizio, Annesi Grazia, Quattrone Aldo
Abstract excerpt
The objective of our study was to investigate the association of two single nucleotide polymorphisms (SNPs) with genetic risk of dementia. In 212 patients with Parkinson's disease (PD), we investigated two polymorphisms within the G-protein coupled receptor kinase 5 (GRK5) gene (rs2420616, rs4752293) to determine a possible risk factor for dementia. We identified two alleles most significantly present in PD...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
