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Article

Association between epidermal growth factor receptor gene polymorphisms and susceptibility to Parkinson's disease.

Neuroscience letters - 25 Sept 2020

Jin Jianing, Xue Li, Bai Xinling, Zhang Xiaona, Tian Qingwu, Xie Anmu

Abstract excerpt

OBJECTIVE: The progressive loss of dopaminergic neurons in the mesencephalic substantia nigra is recognized as an important pathological feature of Parkinson's disease (PD). Several research studies have suggested that the EGFR signaling pathway may play a significant role in the survival and functional development of dopaminergic neurons. Therefore, genetic variations in these pathways may be related with PD...

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PMID: 32712352
DOI: 10.1016/j.neulet.2020.135273

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