Article
Diverse Roles of Axonemal Dyneins in Drosophila Auditory Neuron Function and Mechanical Amplification in Hearing.
Scientific reports - 26 Nov 2015
Karak Somdatta, Jacobs Julie S, Kittelmann Maike, Spalthoff Christian, Katana Radoslaw, Sivan-Loukianova Elena, Schon Michael A, Kernan Maurice J, Eberl Daniel F, Göpfert Martin C
Abstract excerpt
Much like vertebrate hair cells, the chordotonal sensory neurons that mediate hearing in Drosophila are motile and amplify the mechanical input of the ear. Because the neurons bear mechanosensory primary cilia whose microtubule axonemes display dynein arms, we hypothesized that their motility is powered by dyneins. Here, we describe two axonemal dynein proteins that are required for Drosophila auditory neuron...
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