Article

Critical evaluation of the reliability of DNA methylation probes on the Illumina MethylationEPIC BeadChip microarrays

2023-10-17

Abstract excerpt

<title>Abstract</title> <p> DNA methylation (DNAm) plays a crucial role in a number of complex diseases. However, the reliability of DNAm levels measured using Illumina arrays varies across different probes. Previous research primarily assessed probe reliability by comparing duplicate samples between the 450k-450k or 450k-EPIC platforms, with limited investigations on Illumina EPIC arrays. We conducted a compreh...

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Literature Corpus work: 7427e2ec-050f-563a-8776-3d4b6cf3fbde
DOI: 10.21203/rs.3.rs-3068938/v2

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