Article
A case of osteoclast-like giant cell-rich epithelioid glioblastoma with BRAF V600E mutation.
Brain tumor pathology - 1 Jan 2016
Funata Nobuaki, Nobusawa Sumihito, Yamada Ryoji, Shinoura Nobusada
Abstract excerpt
Epithelioid glioblastomas (E-GBMs) are rare, highly aggressive tumors consisting of closely packed tumor cells with smooth, round cell borders and abundant eosinophilic cytoplasm. They tend to affect younger patients compared with conventional GBM. BRAF V600E mutation is characteristically found in approximately 50% of all E-GBMs, compared with a low frequency of this mutation in conventional GBM. Here, we report...
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