Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epithelioid GBMs show a high percentage of BRAF V600E mutation.

The American journal of surgical pathology - 1 May 2013

Kleinschmidt-DeMasters Bette Kay, Aisner Dara L, Birks Diane K, Foreman Nicholas K

Abstract excerpt

BRAF V600E mutation has been identified in up to 2/3 of pleomorphic xanthoastrocytomas (PXAs), World Health Organization grade II, as well as in varying percentages of PXAs with anaplastic features (PXA-A), gangliogliomas, extracerebellar pilocytic astrocytomas, and, rarely, giant cell glioblastoma multiforme (GC-GBMs). GC-GBMs and epithelioid GBMs (E-GBMs) can be histologically challenging to distinguish from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Neoplasms
Share to DNA Mutational Analysis
Share to Glioblastoma

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Immunohistochemistry

Share to In Situ Hybridization, Fluorescence

Share to Microdissection

Share to Proto-Oncogene Proteins B-raf

Share to Reverse Transcriptase Polymerase Chain Reaction

Source

Open in PubMed Open full text

Identifiers

PMID: 23552385
DOI: 10.1097/PAS.0b013e31827f9c5e
PMCID: PMC4610349

Genes

BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epithelioid GBMs show a high percentage of BRAF V600E mutation.PMID 23552385Read ↗

Clinicopathological and genetic association between epithelioid glioblastoma and pleomorphic xanthoastrocytomaSemantic proximity Read ↗

The evolution of pleomorphic xanthoastrocytoma: from genesis to molecular alterations and mimics.Semantic proximity Read ↗

Dysembryoplastic Neuroepithelial Tumors Share with Pleomorphic Xanthoastrocytomas and Gangliogliomas <scp>BRAF<sup>V600E</sup></scp> Mutation and ExpressionSemantic proximity Read ↗

Pleomorphic xanthoastrocytoma, anaplastic pleomorphic xanthoastrocytoma, and epithelioid glioblastoma: Case series with clinical characteristics, molecular features and progression relationship.Semantic proximity Read ↗

Epithelioid glioblastoma arising from pleomorphic xanthoastrocytoma with the BRAF V600E mutation.Semantic proximity Read ↗

Biology and grading of pleomorphic xanthoastrocytoma—what have we learned about it?Semantic proximity Read ↗

A clinicopathologic study of diencephalic pediatric low-grade gliomas with BRAF V600 mutation.Semantic proximity Read ↗

Additional genetic alterations in BRAF-mutant gliomas correlate with histologic diagnoses.Semantic proximity Read ↗

Epithelioid glioblastomas stratify into established diagnostic subsets upon integrated molecular analysis.Semantic proximity Read ↗

BRAF V600E, TERT promoter mutations and CDKN2A/B homozygous deletions are frequent in epithelioid glioblastomas: a histological and molecular analysis focusing on intratumoral heterogeneity.Semantic proximity Read ↗

BRAF V600E-mutated diffuse glioma in an adult patient: a case report and review.Semantic proximity Read ↗

BRAF V600E mutations are common in pleomorphic xanthoastrocytoma: diagnostic and therapeutic implications.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.