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Article

Prediagnosis Plasma Adiponectin in Relation to Colorectal Cancer Risk According to KRAS Mutation Status.

Journal of the National Cancer Institute - 1 Apr 2016

Inamura Kentaro, Song Mingyang, Jung Seungyoun, Nishihara Reiko, Yamauchi Mai, Lochhead Paul, Qian Zhi Rong, Kim Sun A, Mima Kosuke, Sukawa Yasutaka, Masuda Atsuhiro, Imamura Yu, Zhang Xuehong, Pollak Michael N, Mantzoros Christos S, Harris Curtis C, Giovannucci Edward, Fuchs Charles S, Cho Eunyoung, Chan Andrew T, Wu Kana, Ogino Shuji

Abstract excerpt

BACKGROUND: Low levels of adiponectin (ADIPOQ; HGNC ID; HGNC:13633), an adipokine, are associated with obesity, adiposity, excess energy balance, and increased risk of colorectal neoplasia. Given the reported association of increased body mass index (BMI) and low-level physical activity with KRAS-mutated colorectal tumor, we hypothesized that low-level plasma adiponectin might be associated with increased risk of...

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Identifiers

PMID: 26598515
DOI: 10.1093/jnci/djv363
PMCID: PMC4668768

Genes

KRAS
ADIPOQ
BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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