Article
Genetic variants of adiponectin and risk of colorectal cancer.
International journal of cancer - 1 Jul 2015
Song Mingyang, Gong Jian, Giovannucci Edward L, Berndt Sonja I, Brenner Hermann, Chang-Claude Jenny, Curtis Keith R, Harrison Tabitha A, Hoffmeister Michael, Hsu Li, Jiao Shuo, Le Marchand Loic, Potter John D, Schoen Robert E, Seminara Daniela, Slattery Martha L, White Emily, Wu Kana, Ogino Shuji, Fuchs Charles S, Hunter David J, Tworoger Shelley S, Hu Frank B, Rimm Eric, Jensen Majken, Peters Ulrike, Chan Andrew T
Abstract excerpt
Circulating adiponectin has been associated with lower risk of colorectal cancer (CRC). Genome-wide association studies have identified several single-nucleotide polymorphisms (SNPs) associated with adiponectin levels. However, it is unclear whether these SNPs are associated with CRC risk. In addition, previous data on SNPs in the adiponectin pathway and their associations with CRC are inconsistent. Therefore, we...
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