Genomic diversity of Mycobacterium tuberculosis Beijing strains isolated in Tuscany, Italy, based on large sequence deletions, SNPs in putative DNA repair genes and MIRU-VNTR polymorphisms.

Abstract excerpt

The Beijing genotype of Mycobacterium tuberculosis is cause of global concern as it is rapidly spreading worldwide, is considered hypervirulent, and is most often associated to massive spread of MDR/XDR TB, although these epidemiological or pathological properties have not been confirmed for all strains and in all geographic settings. In this paper, to gain new insights into the biogeographical heterogeneity of...

Topics

• Adolescent
• Adult
• Aged
• Bacterial Proteins
• Bacteriological Techniques
• Child
• Child, Preschool
• China
• DNA Repair Enzymes
• Evolution, Molecular
• Female