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New Mycobacterium tuberculosis Beijing clonal complexes in China revealed by phylogenetic and Bayesian population structure analyses of 24-loci MIRU-VNTRs.

Scientific reports - 20 Jul 2017

Zheng Chao, Reynaud Yann, Zhao Changsong, Zozio Thierry, Li Song, Luo Dongxia, Sun Qun, Rastogi Nalin

Abstract excerpt

Beijing lineage of Mycobacterium tuberculosis constitutes the most predominant lineage in East Asia. Beijing epidemiology, evolutionary history, genetics are studied in details for years revealing probable origin from China followed by worldwide expansion, partially linked to higher mutation rate, hypervirulence, drug-resistance, and association with cases of mixed infections. Considering huge amount of data...

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PMID: 28729708
DOI: 10.1038/s41598-017-06346-1
PMCID: PMC5519585

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