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Mycobacterium tuberculosis phylogeography in the context of human migration and pathogen's pathobiology: Insights from Beijing and Ural families.

Tuberculosis (Edinburgh, Scotland) - 1 Jun 2015

Mokrousov Igor

Abstract excerpt

Here, I review the population structure and phylogeography of the two contrasting families of Mycobacterium tuberculosis, Beijing and Ural, in the context of strain pathobiology and human history and migration. Proprietary database (12-loci MIRU-VNTR profiles of 3067 Beijing genotype isolates) was subjected to phylogenetic and statistical analysis. The highest rate (90%) and diversity (HGI 0.80-0.95) of the...

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PMID: 25754342
DOI: 10.1016/j.tube.2015.02.031

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