FibroGENE: A gene-based model for staging liver fibrosis.

doi:10.1016/j.jhep.2015.11.008

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Article

FibroGENE: A gene-based model for staging liver fibrosis.

Journal of hepatology - 1 Feb 2016

Eslam Mohammed, Hashem Ahmed M, Romero-Gomez Manuel, Berg Thomas, Dore Gregory J, Mangia Alessandra, Chan Henry Lik Yuen, Irving William L, Sheridan David, Abate Maria Lorena, Adams Leon A, Weltman Martin, Bugianesi Elisabetta, Spengler Ulrich, Shaker Olfat, Fischer Janett, Mollison Lindsay, Cheng Wendy, Nattermann Jacob, Riordan Stephen, Miele Luca, Kelaeng Kebitsaone Simon, Ampuero Javier, Ahlenstiel Golo, McLeod Duncan, Powell Elizabeth, Liddle Christopher, Douglas Mark W, Booth David R, George Jacob

Abstract excerpt

BACKGROUND & AIMS: The extent of liver fibrosis predicts long-term outcomes, and hence impacts management and therapy. We developed a non-invasive algorithm to stage fibrosis using non-parametric, machine learning methods designed for predictive modeling, and incorporated an invariant genetic marker of liver fibrosis risk. METHODS: Of 4277 patients with chronic liver disease, 1992 with chronic hepatitis C...

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PMID: 26592354
DOI: 10.1016/j.jhep.2015.11.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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