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Article

A liver secretome gene signature-based approach for determining circulating biomarkers of NAFLD severity

19 Oct 2022

Abstract excerpt

Non-invasive biomarkers of non-alcoholic fatty liver disease (NAFLD) supporting diagnosis and monitoring disease progression are urgently needed. The present study aimed to establish a bioinformatics pipeline capable of defining and validating NAFLD biomarker candidates based on paired hepatic global gene expression and plasma bioanalysis from individuals representing different stages of histologically confirmed...

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PMID: 36260611
DOI: 10.1371/journal.pone.0275901

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