Intra-tumoral IFN-γ-producing Th22 cells correlate with TNM staging and the worst outcomes in pancreatic cancer.

doi:10.1042/CS20150437

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Article

Intra-tumoral IFN-γ-producing Th22 cells correlate with TNM staging and the worst outcomes in pancreatic cancer.

Clinical science (London, England : 1979) - 1 Feb 2016

Niccolai Elena, Taddei Antonio, Ricci Federica, Rolla Simona, D'Elios Mario Milco, Benagiano Marisa, Bechi Paolo, Bencini Lapo, Ringressi Maria Novella, Pini Alessandro, Castiglione Francesca, Giordano Daniele, Satolli Maria Antonietta, Coratti Andrea, Cianchi Fabio, Bani Daniele, Prisco Domenico, Novelli Francesco, Amedei Amedeo

Abstract excerpt

PDAC (pancreatic ductal adenocarcinoma) is the fifth leading cause of cancer-related death. The causes of this cancer remain unknown, but increasing evidence indicates a key role of the host immune response and cytokines in human carcinogenesis. Intra-tumoral IL (interleukin)-22 levels have been shown to be elevated in PDAC patients. However, little is known regarding the expression and clinical relevance of Th22...

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PMID: 26590104
DOI: 10.1042/CS20150437

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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