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Article

Expansion of tumor-infiltrating lymphocytes (TIL) from human pancreatic tumors.

Journal for immunotherapy of cancer - 1 Jan 2016

Hall MacLean, Liu Hao, Malafa Mokenge, Centeno Barbara, Hodul Pamela J, Pimiento José, Pilon-Thomas Shari, Sarnaik Amod A

Abstract excerpt

BACKGROUND: We evaluated whether tumor infiltrating lymphocytes (TIL) could be expanded from surgically resected tumors from pancreatic cancer patients. METHODS: Tumors were resected from pancreatic cancer patients. Tumors were minced into fragments and cultured in media containing high dose interleukin-2 (IL-2) for up to 6 weeks. T cell phenotype, activation markers, and reactivity were measured. RESULTS: TIL...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Programmed Cell Death 1 Receptor

Share to T-Cell Antigen Receptor Specificity

Source

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Identifiers

PMID: 27777771
DOI: 10.1186/s40425-016-0164-7
PMCID: PMC5067894

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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