Article
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome medicine - 20 Nov 2015
Scholtalbers Jelle, Boegel Sebastian, Bukur Thomas, Byl Marius, Goerges Sebastian, Sorn Patrick, Loewer Martin, Sahin Ugur, Castle John C
Abstract excerpt
Human cancer cell lines are an important resource for research and drug development. However, the available annotations of cell lines are sparse, incomplete, and distributed in multiple repositories. Re-analyzing publicly available raw RNA-Seq data, we determined the human leukocyte antigen (HLA) type and abundance, identified expressed viruses and calculated gene expression of 1,082 cancer cell lines. Using the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
