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Article

Association of chitotriosidase enzyme activity and genotype with the risk of nephropathy in type 2 diabetes.

Clinical biochemistry - 1 Apr 2016

Elmonem Mohamed A, Amin Hanan S, El-Essawy Riham A, Mehaney Dina A, Nabil Malak, Kamel Laila N, Farid Ibtisam M

Abstract excerpt

OBJECTIVE: The immune-inflammatory system has been implicated in the pathogenesis of diabetic nephropathy; however, many of the mechanisms involved remain unclear. Chitotriosidase enzyme is an active human chitinase and a major protein product of activated macrophages. Although playing an important role in innate and acquired immunity, chitotriosidase involvement in the development of diabetic nephropathy is...

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Identifiers

PMID: 26589000
DOI: 10.1016/j.clinbiochem.2015.11.009

Genes

CHIT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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