Article
[Comparison and clinical application of two methods for determination of plasma chitotriosidase activity].
Zhonghua er ke za zhi = Chinese journal of pediatrics - 1 Nov 2012
Wang Yu, Zhang Hui-wen, Ye Jun, Qiu Wen-juan, Han Lian-shu, Gu Xue-fan
Abstract excerpt
OBJECTIVE: Chitotriosidase (CT) is a plasma biomarker for Gaucher disease (GD), the enzyme activity is usually markedly elevated in plasma of Gaucher patients, and it was reported that levels of plasma chitotriosidase activity was mildly-moderately increased in patients with Niemann-Pick disease (NPD). The aim of this study was to compare chitotriosidase activity using 4-methylumbelliferyl-β-D-N, N',...
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