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Article

Serum Amyloid A Protein Concentration in Blood is Influenced by Genetic Differences in the Cheetah (Acinonyx jubatus).

The Journal of heredity - 1 Mar 2016

Franklin Ashley D, Schmidt-Küntzel Anne, Terio Karen A, Marker Laurie L, Crosier Adrienne E

Abstract excerpt

Systemic amyloid A (AA) amyloidosis is a major cause of morbidity and mortality among captive cheetahs. The self-aggregating AA protein responsible for this disease is a byproduct of serum amyloid A (SAA) protein degradation. Transcriptional induction of the SAA1 gene is dependent on both C/EBPβ and NF-κB cis-acting elements within the promoter region. In cheetahs, 2 alleles exist for a single guanine nucleotide...

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Source

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Identifiers

PMID: 26585380
DOI: 10.1093/jhered/esv089
PMCID: PMC5994965

Genes

SAA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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