Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of the cheetah serum amyloid A1 gene: critical role and functional polymorphism of a cis-acting element.

The Journal of heredity - 1 Jan 2000

Zhang Beiru, Une Yumi, Ge Fengxia, Fu Xiaoying, Qian Jinze, Zhang Pengyao, Sawashita Jinko, Higuchi Keiichi, Mori Masayuki

Abstract excerpt

Amyloid A (AA) amyloidosis is one of the principal causes of morbidity and mortality in captive cheetahs (Acinonyx jubatus), which are in danger of extinction. For practical conservation of this species, therefore, it is critical to elucidate the etiology of AA amyloidosis, especially to understand the mechanisms of transcriptional regulation of serum amyloid A (SAA), a precursor protein of the AA protein. In...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Binding Sites

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cells, Cultured

Share to DNA Mutational Analysis

Share to NF-kappa B

Share to Pedigree

Share to Regulatory Sequences, Nucleic Acid

Share to Serum Amyloid A Protein

Source

Identifiers

PMID: 18375929
DOI: 10.1093/jhered/esn015

Genes

SAA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of the cheetah serum amyloid A1 gene: critical role and functional polymorphism of a cis-acting element.PMID 18375929Read ↗

Serum Amyloid A Protein Concentration in Blood is Influenced by Genetic Differences in the Cheetah (Acinonyx jubatus).Semantic proximity Read ↗

Cheetahs have 4 serum amyloid a genes evolved through repeated duplication events.Semantic proximity Read ↗

Serum amyloid A1: Structure, function and gene polymorphism.Semantic proximity Read ↗

Serum amyloid A, the major vertebrate acute‐phase reactantSemantic proximity Read ↗

A mutation in the SAA1 promoter causes hereditary amyloid A amyloidosis.Semantic proximity Read ↗

Identification of Genetic Associations and Functional Polymorphisms of SAA1 Gene Affecting Milk Production Traits in Dairy Cattle.Semantic proximity Read ↗

A novel single-nucleotide polymorphism at the 5'-flanking region of SAA1 associated with risk of type AA amyloidosis secondary to rheumatoid arthritis.Semantic proximity Read ↗

Relative transcriptional activities of SAA1 promoters polymorphic at position -13(T/C): potential association between increased transcription and amyloidosis.Semantic proximity Read ↗

The Human Serum Amyloid A Protein (SAA) Superfamily Gene Cluster: Mapping to Chromosome 11p15.1 by Physical and Genetic Linkage AnalysisSemantic proximity Read ↗

Genome-wide association study identifies two novel regions at 11p15.5-p13 and 1p31 with major impact on acute-phase serum amyloid A.Semantic proximity Read ↗

The Human Acute‐Phase Serum Amyloid A Gene Family: Structure, Evolution and Expression in Hepatoma CellsSemantic proximity Read ↗

An allele of serum amyloid A1 associated with amyloidosis in both Japanese and Caucasians.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.