Article
Cheetahs have 4 serum amyloid a genes evolved through repeated duplication events.
The Journal of heredity - 1 Jan 2000
Chen Lei, Une Yumi, Higuchi Keiichi, Mori Masayuki
Abstract excerpt
Amyloid A (AA) amyloidosis is a leading cause of mortality in captive cheetahs (Acinonyx jubatus). We performed genome walking and PCR cloning and revealed that cheetahs have 4 SAA genes (provisionally named SAA1A, SAA1B, SAA3A, and SAA3B). In addition, we identified multiple nucleotide polymorphisms in the 4 SAA genes by screening 51 cheetahs. The polymorphisms defined 4, 7, 6, and 4 alleles for SAA1A, SAA3A,...
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