Article
An allele of serum amyloid A1 associated with amyloidosis in both Japanese and Caucasians.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis - 1 Mar 2003
Yamada Toshiyuki, Okuda Yasuaki, Takasugi Kiyoshi, Wang Lishan, Marks Duane, Benson Merrill D, Kluve-Beckerman Barbara
Abstract excerpt
Serum amyloid A1 (SAA1), one of the two isotypes of acute phase SAA, is the predominant precursor to amyloid A (AA) protein, the chief constituent of fibrillar deposits in reactive (AA) amyloidosis. Prolonged hyperexpression of SAA protein accompanying chronic inflammation is critical to, but seems not to be sufficient for, the development of AA amyloidosis. Several previous studies have investigated the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
