Article
Measurement of serum amyloid A1 (SAA1), a major isotype of acute phase SAA.
Clinical chemistry and laboratory medicine - 1 Jan 2006
Xu Yuanyuan, Yamada Toshiyuki, Satoh Takahiko, Okuda Yasuaki
Abstract excerpt
Serum amyloid A (SAA), a plasma precursor of reactive amyloid deposits, is a multigene product. SAA1 and SAA2, with primary structures that are 93% identical (98 of 104 amino acids), behave as acute phase proteins, as demonstrated by their increasing levels in plasma. Heretofore, it has been understood that SAA1 predominates and functions as an isotype in plasma. However, accurate measurements differentiating the...
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