Article
[Analysis of serum amyloid A1 alleles by PCR-RFLP].
Rinsho byori. The Japanese journal of clinical pathology - 1 Jan 1999
Yamada T, Itoh Y, Itoh K
Abstract excerpt
Serum amyloid A1 (SAA1), the acute phase isotype of SAA protein family, preferentially forms amyloid fibrils in reactive amyloidosis. Three alleles (alpha, beta, gamma) have been identified in the SAA1 locus. A recent study suggested the association of SAA1 gamma with amyloidogenesis in Japanese patients with rheumatoid arthritis. In this study, PCR-RFLP method was developed for SAA1 allele analysis. The use of...
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