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Article

Estrogen Receptor-α Knockout Mice.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2016

Antonson Per, Humire Patricia, Gustafsson Jan-Åke

Abstract excerpt

Tissue specific knockout mice are valuable tools to study gene function in vivo. The method uses the Cre/loxP system in which loxP sites are cloned into the genome surrounding one or more exons of a gene and the targeted exon(s) are deleted when the Cre enzyme is expressed. Mouse lines that are prepared for the generation of knockout ERα mice have been developed independently by many research groups and the...

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PMID: 26585154
DOI: 10.1007/978-1-4939-3127-9_33

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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