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Article

Bioengineered vocal fold mucosa for voice restoration.

Science translational medicine - 18 Nov 2015

Ling Changying, Li Qiyao, Brown Matthew E, Kishimoto Yo, Toya Yutaka, Devine Erin E, Choi Kyeong-Ok, Nishimoto Kohei, Norman Ian G, Tsegyal Tenzin, Jiang Jack J, Burlingham William J, Gunasekaran Sundaram, Smith Lloyd M, Frey Brian L, Welham Nathan V

Abstract excerpt

Patients with voice impairment caused by advanced vocal fold (VF) fibrosis or tissue loss have few treatment options. A transplantable, bioengineered VF mucosa would address the individual and societal costs of voice-related communication loss. Such a tissue must be biomechanically capable of aerodynamic-to-acoustic energy transfer and high-frequency vibration and physiologically capable of maintaining a barrier...

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Identifiers

PMID: 26582902
DOI: 10.1126/scitranslmed.aab4014
PMCID: PMC4669060

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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