Article
A genomic approach to understand interactions between Streptococcus pneumoniae and its bacteriophages.
BMC genomics - 18 Nov 2015
Leprohon Philippe, Gingras Hélène, Ouennane Siham, Moineau Sylvain, Ouellette Marc
Abstract excerpt
BACKGROUND: Bacteriophage replication depends on bacterial proteins and inactivation of genes coding for such host factors should interfere with phage infection. To gain further insights into the interactions between S. pneumoniae and its pneumophages, we characterized S. pneumoniae mutants selected for resistance to the virulent phages SOCP or Dp-1. RESULTS: S. pneumoniae R6-SOCP(R) and R6-DP1(R) were highly...
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