Article
The role of genomics in global cancer prevention.
Nature reviews. Clinical oncology - 1 Feb 2021
Ginsburg Ophira, Ashton-Prolla Patricia, Cantor Anna, Mariosa Daniela, Brennan Paul
Abstract excerpt
Despite improvements in the understanding of cancer causation, much remains unknown regarding the mechanisms by which genomic and non-genomic factors initiate carcinogenesis, drive cell invasion and metastasis, and enable cancer to develop. Technological advances have enabled the analysis of whole genomes, comprising thousands of tumours across populations worldwide, with the aim of identifying mutation...
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