Article
MicroRNAs: tools for cancer diagnostics.
Gut - 1 Nov 2009
Paranjape T, Slack F J, Weidhaas J B
Abstract excerpt
Recently, a novel class of global gene regulators called microRNAs (miRNAs), were identified in both plants and animals. MiRNAs can reduce protein levels of their target genes with a minor impact on the target genes' mRNAs. Accumulating evidence demonstrates the importance of miRNAs in cancer. MiRNAs that are overexpressed in cancer may function as oncogenes, and miRNAs with tumour suppressor activity in normal...
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