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Article

Left-Right Axis Differentiation and Functional Lateralization: a Haplotype in the Methyltransferase Encoding Gene SETDB2 Might Mediate Handedness in Healthy Adults.

Molecular neurobiology - 1 Nov 2016

Ocklenburg Sebastian, Arning Larissa, Gerding Wanda M, Hengstler Jan G, Epplen Jörg T, Güntürkün Onur, Beste Christian, Akkad Denis A

Abstract excerpt

Handedness is a multifactorial trait, and genes contributing to the differentiation of the left-right axis during embryogenesis have been identified as a major gene group associated with this trait. The methyltransferase SETDB2 (SET domain, bifurcated 2) has been shown to regulate structural left-right asymmetry in the vertebrate central nervous system by suppressing fgf8 expression. Here, we investigated the...

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PMID: 26572639
DOI: 10.1007/s12035-015-9534-2

Genes

SETDB2
SET
SETDB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Left-Right Axis Differentiation and Functional Lateralization: a Haplotype in the Methyltransferase Encoding Gene SETDB2 Might Mediate Handedness in Healthy Adults.PMID 26572639Read ↗

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