Article

Exome-wide analysis implicates rare protein-altering variants in human handedness

2023-06-01

Abstract excerpt

Handedness is a manifestation of brain hemispheric specialization. Left-handedness occurs at increased rates in neurodevelopmental disorders. Genome-wide association studies have identified common genetic effects on handedness or brain asymmetry, which mostly involve variants outside protein-coding regions and may affect gene expression. Implicated genes include several that encode tubulins (microtubule components...

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Literature Corpus work: e68ba440-53d9-58e6-854a-1cea062e09cd
DOI: 10.1101/2023.05.31.543042

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