The SETDB2 locus: evidence for a genetic link between handedness and atopic disease.

doi:10.1038/s41437-017-0004-7

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Article

The SETDB2 locus: evidence for a genetic link between handedness and atopic disease.

Heredity - 1 Jan 2018

Crespi Bernard, Read Silven, Hurd Peter

Abstract excerpt

The gene SETDB2, which mediates aspects of laterality in animal model systems, has recently been linked with human handedness as measured continuously on a scale from strong left to strong right. By contrast, it was marginally associated with a left-right dichotomous measure, and it showed no evidence of association with absolute handedness strength independent of direction. We genotyped the SETDB2...

Topics

Adolescent
Female
Functional Laterality
Gene Frequency
Genetic Predisposition to Disease
Genotype
Histone-Lysine N-Methyltransferase
Humans
Hypersensitivity
Immunoglobulin E
Linkage Disequilibrium
Male
Polymorphism, Single Nucleotide
Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 29234167
DOI: 10.1038/s41437-017-0004-7
PMCID: PMC5837111

Genes

SETDB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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