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Article

Endochondral ossification pathway genes and postmenopausal osteoporosis: Association and specific allele related serum bone sialoprotein levels in Han Chinese.

Scientific reports - 16 Nov 2015

Zhang Yunzhi, Liu Haiyan, Zhang Chen, Zhang Tianxiao, Zhang Bo, Li Lu, Chen Gang, Fu Dongke, Wang KunZheng

Abstract excerpt

Osteoporosis is a systemic skeletal disorder characterized by reduced bone mineral density (BMD) and disrupted bone architecture, predisposing the patient to increased fracture risk. Evidence from early genetic epidemiological studies has indicated a major role for genetics in the development of osteoporosis and the variation in BMD. In this study, we focused on two key genes in the endochondral ossification...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26568273
DOI: 10.1038/srep16783
PMCID: PMC4645187

Genes

IBSP
PTHLH

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