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Article

Contribution of the sclerostin domain-containing protein 1 (SOSTDC1) gene to normal variation of peak bone mineral density in Chinese women and men.

Journal of bone and mineral metabolism - 1 Sept 2011

He Jin-Wei, Yue Hua, Hu Wei-Wei, Hu Yun-Qiu, Zhang Zhen-Lin

Abstract excerpt

A genome-wide linkage analysis in Chinese families revealed a significant quantitative trait loci on chromosome 7p21.1 for femoral neck bone mineral density (BMD) (LOD = 3.68), and a potential candidate gene, sclerostin domain-containing protein 1 (SOSTDC1), is located in this region. SOSTDC1 belongs to a class of bone morphogenetic protein (BMP) antagonists that bind BMPs and regulate their signaling. We...

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Identifiers

PMID: 21221677
DOI: 10.1007/s00774-010-0253-5

Genes

SOSTDC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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