Article
BRCA Mutation-Related and Claudin-Low Breast Cancer: Blood Relatives or Stepsisters.
Pathobiology : journal of immunopathology, molecular and cellular biology - 1 Jan 2016
Madaras Lilla, Balint Nora, Gyorffy Balazs, Tokes Anna-Maria, Barshack Iris, Yosepovich Ady, Friedman Eitan, Paluch-Shimon Shani, Zippel Dov, Baghy Kornelia, Timar Jozsef, Kovalszky Ilona, Kulka Janina, Szasz Attila Marcell
Abstract excerpt
BACKGROUND: BRCA mutation-associated (BRCAmut) breast cancer represents a heterogeneous group displaying certain molecular features. Claudin-low breast cancers (CLBC) overlap with characteristics of BRCAmut tumors; therefore, we have investigated whether these are identical subtypes. METHODS: Using public gene expression data, CLDN, CDH1, 9-cell line claudin-low predictor (9CLCLP) and PAM50 expression was...
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