Article
Improved rat genome gene prediction by integration of ESTs with RNA-Seq information.
Bioinformatics (Oxford, England) - 1 Jan 2015
Li Liping, Chen Enguo, Yang Chun, Zhu Jun, Jayaraman Pushkala, De Pons Jeffrey, Kaczorowski Catherine C, Jacob Howard J, Greene Andrew S, Hodges Matthew R, Cowley Allen W, Liang Mingyu, Xu Haiming, Liu Pengyuan, Lu Yan
Abstract excerpt
MOTIVATION: RNA-Seq (also called whole-transcriptome sequencing) is an emerging technology that uses the capabilities of next-generation sequencing to detect and quantify entire transcripts. One of its important applications is the improvement of existing genome annotations. RNA-Seq provides rapid, comprehensive and cost-effective tools for the discovery of novel genes and transcripts compared with expressed...
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