Article
A review of animal models of obsessive-compulsive disorder: a focus on developmental, immune, endocrine and behavioral models.
Expert opinion on drug discovery - 1 Jan 2016
Grados Marco, Prazak Michael, Saif Aneeqa, Halls Andrew
Abstract excerpt
INTRODUCTION: Obsessive-compulsive disorder (OCD) is a neuropsychiatric condition characterized by intrusive thoughts (obsessions) and/or repetitive behaviors (compulsions). Several models of OCD exist, many which employ behaviors such as over-grooming or hoarding as correlates for compulsive behaviors - often using a response to serotonergic agents as evidence for their validity. Recent discoveries in the...
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