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Article

Compulsive behavior in the 5-HT2C receptor knockout mouse.

Physiology & behavior - 1 Apr 2003

Chou-Green Jennifer M, Holscher Todd D, Dallman Mary F, Akana Susan F

Abstract excerpt

The efficacy of serotonergic pharmacotherapy indicates that serotonin (5-HT) plays a role in the treatment, if not the etiology, of obsessive-compulsive disorder (OCD). While some clinical evidence implicates 5-HT(2C) receptors in this disorder, a definitive function has yet to be validated. We hypothesized that 5-HT(2C) receptor knockout (KO) mice may display compulsive-like behavior. This paper describes...

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Source

Identifiers

PMID: 12782219
DOI: 10.1016/s0031-9384(03)00047-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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