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Article

Probing compulsive and impulsive behaviors, from animal models to endophenotypes: a narrative review.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Feb 2010

Fineberg Naomi A, Potenza Marc N, Chamberlain Samuel R, Berlin Heather A, Menzies Lara, Bechara Antoine, Sahakian Barbara J, Robbins Trevor W, Bullmore Edward T, Hollander Eric

Abstract excerpt

Failures in cortical control of fronto-striatal neural circuits may underpin impulsive and compulsive acts. In this narrative review, we explore these behaviors from the perspective of neural processes and consider how these behaviors and neural processes contribute to mental disorders such as obsessive-compulsive disorder (OCD), obsessive-compulsive personality disorder, and impulse-control disorders such as...

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Identifiers

PMID: 19940844
DOI: 10.1038/npp.2009.185
PMCID: PMC3055606

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