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Article

Characterization of Transcriptional Repressor Gene MSX1 Variations for Possible Associations with Congenital Heart Diseases.

PloS one - 1 Jan 2015

Li Fei-Feng, Han Ying, Shi Shuai, Li Xia, Zhu Xi-Dong, Zhou Jing, Shao Qing-Liang, Li Xue-Qi, Liu Shu-Lin

Abstract excerpt

BACKGROUND: The human heart consists of several cell types with distinct lineage origins. Interactions between these cardiac progenitors are very important for heart formation. The muscle segment homeobox gene family plays a key role in the cell morphogenesis and growth, controlled cellular proliferation, differentiation, and apoptosis, but the relationships between the genetic abnormalities and CHD phenotypes...

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Topics

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Share to Cell Differentiation
Share to Child, Preschool

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Association Studies

Share to Heart Defects, Congenital

Share to Homeodomain Proteins

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Share to MSX1 Transcription Factor

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Source

Open in PubMed Open full text

Identifiers

PMID: 26556783
DOI: 10.1371/journal.pone.0142666
PMCID: PMC4640503

Genes

MSX1
MSX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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